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SeQuent® DCBs

Your way to confidence

Enter the world of SeQuent^® DCB treatment with cutting-edge balloon technology and a proven leader at your side – for more drug options, more clinical data, high-quality support and the confidence you’re aiming for.

Join B. Braun @ EuroPCR 2025

Visit us at booth M16, attend our two symposia and meet the global experts on site. (May 20-23, 2025 in Paris)

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Cooperation

Cardiovascular News

New Momentum in DCB-PCI - Insights from B. Braun DCB Day

At the recent DCB Days nine esteemed DCB experts like Raban Jeger and Robert Byrne shared their key concepts and insights on the principle of leaving nothing behind in coronary vessels. The course covered key concepts and practical applications, allowing attendees to deepen their understanding and enhance their skills in this area.

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Paclitaxel coated balloon

SeQuent® Please NEO – Master of evidence

The SeQuent® Please NEO is a drug coated balloon catheter for treating stenosis of coronary arteries with PTCA, while leaving nothing behind. The PCB has a matrix coating (PACCOCATH®-Technology), which helps to keep coronary arteries open by inhibiting smooth muscle cell proliferation and migration.

B. Braun´s paclitaxel coated balloon SeQuent® Please NEO is the best investigated DCB [1] in the field of percutaneous coronary interventions (PCI). It has demonstrated its convincing performance, efficacy and safety in more than 110 published studies (including more than 35 RCTs) – with over 25,000 documented patients, conducted in more than 20 countries.

SeQuent® Please NEO – Paclitaxel coated balloon

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Publications for SeQuent® Please / NEO

The coronary DCB has been investigated in more than 110 studies with over 25,000 documented patients, conducted in more than 20 countries.

Download studies now

Sirolimus coated balloon

SeQuent® SCB – Pioneer of proof

B. Braun´s new sirolimus coated balloon is the first SCB backed up with published randomized clinical trials for ISR and de-novo lesions.^{[2], [3], [4]}SeQuent® SCB now offers new implant-free options for treating coronary ISR and de-novo lesions, providing excellent results in targeted drug delivery and sirolimus persistence. The combination of sirolimus and BHT (Butylated Hydroxy Toluol) creates the desired crystalline sirolimus modification to reach best results regarding sirolimus vessel wall content compared to other excipients.^[5]

SeQuent® SCB is the only coronary sirolimus coated balloon with published RCTs: 2 RCTs on ISR lesions, 1 RCT on de-novo lesions
Multicenter data from Europe and Asia
Ongoing studies for de-novo and real world

How and when should I best use DCBs

Watch the expert videos

DCB may be an appealing strategy in diabetic patients
„How using DCBs can „open up a new world“ for PCI
“DCBs and stents are complementary devices and not the opposite.”
Ready for primetime? The future role of drug-coated balloons in PCI
Important to utilise DCBs with strongest possible data
DCB and the good night sleep

Drug Coated Balloon Online Trainings

Want to learn more about DCBs and the importance of lesion preparation in PCI? Register here for exclusive access to recordings of our Drug Coated Balloon online training courses.

Study summaries SeQuent® Please / NEO

Randomized controlled trials

Not randomized controlled trials & observational studies

Clinical evidence SeQuent® SCB

Preclinical work and randomized controlled trials

Related products

SeQuent® Please NEO

Next generation coronary Drug Coated Balloon to treat vascular stenosis

SeQuent® SCB

Sirolimus coated balloon catheter for PTCA

Get in touch with our Coronary Drug Coated Balloon experts

References

All numbers referring to clinical coronary trials on PCBs, patients enrolled therein and countries in which these trials were conducted, are based on a PubMed literature search conducted with due diligence in February/March 2022. (Data on file at B. Braun)
Ali RM et al J Am Coll Cardiol Intv 2019;12:558-66
Scheller B et al. Circ Cardiovasc Interv. 2022 Sep;15(9):e012305.
Ahmad WAW et al. JACC Cardiovasc Interv. 2022 Apr 11;15(7):770-779
Clever et al. Circ Cardiovasc Interv. 2016 Apr;9(4):e003543.
Kleber FX et al. Clin Res Cardiol. 2013 Nov;102(11):785-97.
Jeger RV et JACC Cardiovasc Interv. 2020 Jun 22;13(12):1391-1402.

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